Arsenal will spend three days promoting the club in the capital Hanoi from July 15-17 and will field a full-strength team against the national side at the My Dinh National Stadium on the final day, the Vietnam Football Federation said on its website.
Arsenal say they have an especially big following in the country.
The Asia trip will be Arsenal's third tour to the Far East in three years.
Arsenal's chief commercial officer Tom Fox said: "Arsenal Football Club has so many loyal supporters all across Asia.
"The Club and the players have hugely enjoyed successful pre-season visits to Asia in the past two years, and we are all looking forward to bringing the team to this region again this year."
Rivals Chelsea, Manchester United and Liverpool are also making trips this summer to Southeast Asia, where top European clubs have huge followings and draw large revenues from television and merchandising.
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